- Exit-of-mitosis Mutants
- cdc14-ts
- cdc14-ts GAL-SIC1
- cdc14ts then GAL-SIC1
- cdc14-ts cdh1∆
- cdc14-ts sic1∆
- cdc14-ts GAL-CLN2
- net1-ts
- net1-ts in nocodazole
- net1∆ cdc20-ts
- tem1∆ net1-ts
- cdc15∆ net1-ts
- cdc15∆ net1-ts cdh1∆
- GAL-NET1
- GAL-CDC14
- GAL-NET1 GAL-CDC14
- cdc15-ts multicopy CDC14
- tem1-ts multicopy CDC14
- TAB6-1
- TAB6-1 cdc15∆
- TAB6-1 clb5∆ clb6∆
- TAB6-1 CLB1 clb2∆
cdc14-ts GAL-SIC1
debug: ,
test user =
test db =
Simulation:
Change of parameters: ks14=0, ksc1'=0.12, MDT=150.
Length of G1 phase: 121.5 min.
Arrest: Telophase arrest.
Experiments:
Fitzpatrick, P.J., Toyn, J.H., Millar, J.B. and Johnston, L.H. (1998). DNA replication is completed in Saccharomyces cerevisiae cells that lack functional Cdc14, a dual-specificity protein phosphatase. Mol. Gen. Genet. 258:437-441.
[Abstract] [Article]
[Abstract] [Article]
Jaspersen, S.L., Charles, J.F., Tinker-Kulberg, R.L., and Morgan, D.O. (1998). A late mitotic regulatory network controlling cyclin destruction in Saccharomyces cerevisiae. Mol. Biol. Cell 9:2803-2817.
[Abstract] [Article]
[Abstract] [Article]
Yuste-Rojas, M. and Cross, F.R. (2000). Mutations in CDC14 result in high sensitivity to cyclin gene dosage in Saccharomyces cerevisiae. Mol. Gen. Genet. 263:60-72.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Jaspersen, Table 4, weakly rescued. Fitzpatrick, Fig. 2. Yuste-Rojas, Fig. 3D, weakly rescued.
Comments: